Severe asthma’s heterogeneity makes finding treatment difficult. Up to 15 percent of people with asthma do not respond to standard inhaled corticosteroid therapy, resulting in close to 2 million emergency room visits, 500,000 hospitalizations, and 4,000 asthma deaths annually. But treatments for individual patients have been found. We asked asthma specialists and patients to share their most challenging asthma cases and the therapies that improved patients’ quality of life. Read their stories by clicking on the pictures below.